Set your bottle where your morning already happens. Semaine grew out of one household tracking painful periods and now makes plant based formulas for cycle, gut, mood and bladder. Founders Lauren Lee and Matt Crane talk timing, pairing and habit cues, plus what testing sits behind each lot.

Semaine traces to a kitchen table in a home dealing with endometriosis. That is the detail to hold first, because it explains why the label reads like instructions for a week, not a slogan for a lifetime. Lar, the wife of co-founder Matt Crane, lived through years when severe period pain was brushed aside and sent home without a next step.

Lauren Lee serves as chief executive and co-founder. Matt Crane serves as co-founder and chief science officer. Lar anchors the origin, after long experience with draining periods and endometriosis. Twin sisters Cath and Lar carry the same DNA and the same endometriosis diagnosis. What the sisters lacked in common, the company says, was a workable plan.

What Semaine sells today follows that household pattern. The range covers plant based support for period symptoms, PMS, hormone balance, gut health and bladder health. The company reports that finished blends are clinically studied by an independent third party lab, and that each supplement is third party tested for quality and purity. It reports guidance from a medical advisory board spanning gynecology, urology and other fields. Beneath the mission wording sits a routine logic. Take the right capsule in the right window, then stop or keep going as the panel directs.

Your about page states that Lar spent years with dismissed symptoms and incomplete answers before a plant based formula led to her first pain free period, how should a buyer read a label after hearing that story.

I am Lauren, and I will open here because Matt and I felt it from separate sides. Lar is family to us. We saw her told that crushing pain counted as normal, then left without a plan to try. Years of brushed off symptoms and partial answers change how you scan any package. You skip the front. You flip it over.

When Matt applied his training to mix a plant based blend and Lar then logged her first pain free period, we did not assume we held a fix for all. We felt we owed it proper testing. That is why we phrase it as building the options we could not locate, meant for every woman who merits them. To me, a panel must display its proof. It should name what is inside, the dose, the form, and the checks behind it. Our shopper scans the Supplement Facts panel plus the other ingredients list. She often shops for herself and for others at home. She reorders for years only when a bottle proves its worth. That proof is our job.

Your site states that you run clinical studies on your formulas with an independent, third party lab, and that you have done so since day one, which morning or evening habits make that kind of study easier to trust.

I am Matt. We test finished formulas in clinical studies run with an independent, third party lab. Concrete data, not only our assurance. Testing our blends in clinical studies since day one was a decision from before growth. It adds cost. It adds time. We viewed it as the price of asking for confidence.

To be precise, we assess the blend as packaged, not just components alone. The lab stands apart, so methods and collection stay outside our staff. That structure lets us report what study volunteers noted under set conditions. It cannot show what a capsule may do for you at home. Any trial is bounded by sample, duration and group. We relay results as the company relays them, while the bottle gives contents and use steps. We refuse to stretch a trial past its reach. We keep advisors in gynecology, urology and related areas engaged so learning reflects only what was actually tracked.

You name twin sisters Cath and Lar who share DNA and an endometriosis diagnosis but did not share a clear answer, what does that teach a household trying to stack products for more than one person.

I am Matt, and the science side stays with me here. Identical DNA, matching diagnosis, separate lived pattern. That taught us that cycle health is not a couple hormones, it is an integrated system. Hormones shift by day, by week, by month and across a lifespan. Our name holds that too. Semaine means week in French.

We had no wish to sell a single cramp capsule and stop. What started around period pain widened into restoring balance at the root. That sentence steers mixing. We treat cycle, gut, bladder and mood as linked. We aim at the source of what you sense, not only outward signs. Source work, not surface work. Simple to print. Tough to evidence. For us it calls for researching the completed formula, not merely one herb alone, plus plain guidance on when to take it and when to pause. Born from love. Backed by biology. We hold ourselves to that bar.

Three Semaine bottles styled on a marble counter with greenery.
Three Semaine bottles styled on a marble counter with greenery. Photo · Semaine

Your brand also states that every supplement is third party tested for quality and purity, can you trace the order for a reader who wants to anchor a new bottle to a lot number.

I am Matt again. The sequence runs from farm or fermenter, to drying and extraction, to powder or oil, to encapsulation, to lot testing. A farmer gathers the botanical. That harvest batch is dried for moisture control. Next comes extraction, where a solvent or alternate technique draws the desired fraction into a powder or oil with a defined extract ratio or standardized marker, laid out in our spec sheet and then on the panel where rules require.

That bulk powder ships with documents. We then mix to fill weight, fill capsules, and quarantine the finished lot. An outside lab examines that lot for identity, potency and contaminants, covering heavy metals and microbes where relevant, then grants a certificate of analysis. The certificate attaches to one lot and batch number, never to the label at large. So when we say each supplement is third party tested for quality and purity, we point to that finished lot review. If a shopper asks the exact source of a botanical, the lot file should tie grower, harvest, extract and final capsule. That paper chain is what we keep working to display.

Your PMS Relief Capsule at 32.99 dollars states that you take it when you feel your first PMS symptoms start and stop once your period is finished, how do you set that window inside a busy month.

I am Lauren. We created this because we rely on it ourselves. The PMS Relief Capsule connects to our start. It is meant to soothe menstrual signs such as mood swings, bloating, and cramps, using the brand’s stated wording. Those terms sit on the box and the product page. They note the intended support area, not a pledge for your cycle.

We chose episodic timing because it tracked Lar’s rhythm. Signs climbed, then cleared. Taking it every day of the month did not fit her flow. So use steps say begin at first PMS signs and halt when bleeding ends. That also keeps buying math simple. One pack contains a set count for that span. The two pack at 64.98 dollars and three pack at 89.97 dollars repeat the same cadence. We stayed plant based because those inputs we could follow, source steadily, and assess as a complete mix. When someone seeks everyday backing for mood, energy and cravings, we direct them toward a daily blend instead.

Born from love. Backed by biology.

Lauren Lee and Matt Crane

Your Hormone Balance at 36.99 dollars combines three botanicals plus essential vitamins and minerals for daily mood, energy and cravings support, where does it sit in a daily stack and what pairs well with it.

I am Matt. Front space is tight. The back panel carries detail. Our task is to keep that back panel precise. For Hormone Balance, contents list three botanicals plus essential vitamins and minerals. Every item carries a form, a plant part, a per serving dose, plus an extract ratio or standardization when relevant. That precision lets a label reader set one bottle beside another.

Choice begins with traditional use plus published research, then turns to sourcing. Will a grower hit the same marker crop after crop. Will the extractor preserve that marker absent a solvent swap we would reject. Will the final lot pass our quality and purity spec. Absent that, a botanical stays out, no matter how appealing the story. The other ingredients row counts equally. Shell, fill aids, color. We trim where possible, and we disclose the rest. Clean and pure are assertions. We aim to pair them with files.

Your Urinary Tract Cleanse and Protect at 30.99 dollars centers on Anthocran Phytosome cranberry described as 3x better absorbed and states that you address the biofilm while hibiscus supports immunity in your positioning, when in the day do you take it and what do you space apart.

I am Matt. I will keep near the panel here. The formula builds around Anthocran Phytosome cranberry, a cranberry extract in phytosome format designed to aid uptake. The listing carries 3x better absorbed. That ratio points to the supplier’s own data on that format, not to our capped blend by itself. We repeat it as the company phrases it.

What we can follow is extract identity, per serving amount, everyday use for urinary support, plus finished lot checks for quality and purity. What we say on role stays tight. Most urinary products target the bacteria. We target the biofilm. Steady daily effort, at the root. That wording marks intended focus, not assured effect. What stays less visible, candidly, is a complete seasonal field chart for each crop. We can list extract plus form plus lot. Full farm level mapping across seasons for each botanical is the next file to publish, and we own that gap.

Single Semaine PMS Relief gummies bottle on white.
Single Semaine PMS Relief gummies bottle on white. Photo · Semaine

You expanded from periods into bladder, gut and perimenopause and menopause support, including a 40 plus line and a Microbiome Protocol, how does a reader build a simple routine across those shelves without doubling up.

I am Lauren. For a steady routine, think of womens health as one connected system, not just a few hormones. That view made growth feel logical. Bladder needs, gut needs, hormone shifts and menopause signs kept surfacing in shared homes. Women kept hearing those signs counted as normal. We reject that reply. We reject masking surface signs apart from root work. We reject marketing science absent third party clinical studies and quality testing.

We preserve clarity by repeating the same file order. Every fresh mix follows the same path. Spec, completed blend research via an outside lab where noted, lot review, plain use steps. The Peri and Meno Essentials at 36.99 dollars is reported as clinically studied to ease 14 measures of menopause, covering hot flashes, mood swings and hair thickness, in brand wording. The Pre and Probiotic for Women at 32.99 dollars is reported to carry ginger extract for digestion, nausea, bloating and intestinal discomfort. We do not blend their accounts. Each box rests on its separate lot file.

Your team page notes that many of the team are women and half live with chronic health conditions, with a medical advisory board in gynecology, urology and beyond, what habit cues did that team build into the directions.

I am Lauren. It guides what we leave unsaid. When half our staff manages chronic illness, hype lands close to home. We have stood at a drugstore shelf reading while hurting. So we phrase steps as plain cues. When to begin. When to end. Daily or episodic. With food or as directed. We mark plant based where accurate. We mark third party where accurate.

The board keeps wording exact. Gynecology, urology and beyond means bladder wording gets urology review, cycle wording gets gynecology review. Members check study phrasing and learning content so we outline what was tested absent turning it into guidance for your diagnosis. We Made This Because We Need It is lived for us, not a tag. It means tester and buyer are often one person in our office. That lifts the bar for paperwork, not just prose.

Semaine is French for week, which you link to hormones changing daily, weekly, monthly and through life, how would you track whether a week by week routine is actually holding.

I am Matt and Lauren together on this, since it spans plant and pledge. It would call for listing grower and harvest lot, naming drying plus extraction style with ratio or standardized marker, naming the capsule site and fill weight, and sharing the finished lot certificate of analysis covering heavy metals and microbe screens. Then tying that bundle to the lot code stamped on the jar.

We hold portions of that packet now through specs and outside testing. The seasonal grower chart across a broader set is still in progress, as crops rotate and vendors turn over. They could not find a clear answer to hang a morning routine on, so they built one for themselves and for women told their symptoms were normal. That line still leads us. Any answer must be traceable. Where a stage stays unseen, we name it, and we note what full display would need. That is how a week to week plan keeps a place for years.

Closing note from the desk

What remains after this talk is sequence. The founders open with a family account, then shift fast to lot codes, extract types and outside labs. Wording stays compact on use, on the pack and in steps, and widens only to name purpose.

Semaine aims to restore balance at the root and help women feel more like themselves with clinically studied blends. Put in routine terms, that equals plant based mixes, completed blend research through an independent lab as reported, lot review for quality and purity as reported, and panels that show a busy reader when to start and when to pause. Talk with a clinician or pharmacist if you take medication, are pregnant, or manage a condition.

Product spotlight

Take PMS Relief Capsule each month, priced at 32.99 dollars for one pack, 64.98 dollars for two pack and 89.97 dollars for three pack. Support for menstrual signs such as mood swings, bloating and cramps in brand wording. Pair with your symptom calendar. Start with first PMS signs and stop when the period ends, as directed.

Keep Urinary Tract Cleanse and Protect by the sink, priced at 30.99 dollars for one pack, 61.98 dollars for two pack and 92.97 dollars for three pack. Daily support built around Anthocran Phytosome cranberry with hibiscus in brand positioning. Anchor to breakfast and water, take daily for urinary support as the label directs, with lot testing for quality and purity as reported.

Interview by

Ashley Chen

Ashley produces the interviews at The Daily Capsule: the research, the question lists, the follow-ups. Her favorite question comes last, when she asks a founder exactly when, and with what, they take their own product.

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